Mechanism of Liangxue Jiedu oral liquid in the treatment of psoriasis vulgaris based on network pharmacology and molecular docking.

ABSTRACT: This study aims to investigate the therapeutic mechanism of Liangxue Jiedu oral liquid in treating psoriasis vulgaris using the network pharmacology and molecular docking. Active compounds and their corresponding targets of Liangxue Jiedu oral liquid were obtained using the TCMSP database, and protein and gene names were standardized using the Uniprot database. A medicinal material-active compound-target interaction network was structured utilizing Cytoscape software. The targets associated with psoriasis vulgaris were collected from the GeneCards database, and a protein-protein interaction network of common targets of the disease and active compounds was established using the STRING database with core targets screened via Cytoscape software package. Gene Ontology and Kyoto Encyclopedia of

SUBMITTER: Yang J 

PROVIDER: S-EPMC12582814 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature