Phthalates and bisphenols early-life exposure, and childhood allergic conditions: a pooled analysis of cohort studies.

ABSTRACT:

Background

Exposure to plastic additives, such as phthalates and bisphenols, has been associated with a higher risk of allergic conditions, but the evidence is inconsistent for children younger than five.

Objective

To examine the association between pre- and postnatal urinary phthalates and bisphenols, and allergic conditions, and potential effect modification by sex, in pre-school children, through a pooled analysis.

Methods

We pooled data from the Barwon Infant Study (Australia), the Canadian Healthy Infant Longitudinal Development Study (Canada), the Health Outcomes and Measures of the Environment (United States) and the Environmental Influences on Child Health Outcomes-wide cohorts (United States). Urinary phthalates and bisphenols were measured during pregnancy a

SUBMITTER: Boissiere-O'Neill T 

PROVIDER: S-EPMC12583191 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature