Central retinal volume derived from optical coherence tomography as a potential predictor of mortality in the old-aged population- results from the German AugUR study.

ABSTRACT:

Purpose

To estimate mortality risk depending on central retinal volume (CRV) from optical coherence tomography (OCT) in a German cohort of the old-aged population.

Methods

In the AugUR study, a prospective population-based cohort study in individuals aged 70-95 years at baseline, we conducted multimodal retinal imaging, including spectral-domain OCT. Heidelberg Spectralis-derived CRV measurements from first examinations of 2,166 participants were included in the analyses. Within the observation period (median 5.9-years), 374 participants died. Association between CRV at baseline and mortality was analysed with Kaplan-Meier curves and Cox proportional hazard regression.

Results

Decrease in CRV was associated with increased all-cause mortality risk. In a full model with

SUBMITTER: Stark KJ 

PROVIDER: S-EPMC12583423 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature