Keratoconus prevalence in astigmatic adolescents: findings from a nationwide screening setting.

ABSTRACT:

Objectives

To assess the association between varying levels of astigmatism and the likelihood of keratoconus diagnosis in adolescents.

Methods

This cross-sectional study included 896,377 adolescents aged 16-20 years who underwent a standardised medical assessment between 2011 and 2022, including refraction and topography/tomography in cases where astigmatism above 2.00 dioptres (D) was observed. Astigmatism was categorised into five groups: None, 0.75- < 2.00 D, 2.00- < 3.00 D, 3.00- < 5.00 D, and ≥5.00 D. Logistic regression models were used to assess the association between astigmatism and keratoconus diagnosis. Receiver Operating Characteristic (ROC) curve analysis was performed to evaluate the discriminatory ability of cylinder power in detecting keratoconus.

Results<

SUBMITTER: Safir M 

PROVIDER: S-EPMC12583458 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature