The association between whole-blood lead concentration and all-cause or cardiovascular disease mortality in hypertensive patients.

ABSTRACT: The purpose of this study was to examine the relationship between whole-blood lead levels and mortality in a hypertensive population in the United States. In our study, 8364 subjects aged 20 years and older were included. We used a weighted COX proportional risk regression model to calculate risk ratios (HR) and 95% confidence intervals (CI) for blood lead and mortality. The relationship between whole-blood lead levels and mortality was described by a restricted cubic spline curve. Kaplan Meier curves were used to describe the relationship between survival time and survival in study subjects, and all-cause mortality was analyzed in subgroups. Using the lowest quartile (Q1) as a reference, the HRs for all-cause mortality in model 3 (Q2, Q3, and Q4) were 1.05 (95% CI 0.84-1.32), 1.10 (95% CI

SUBMITTER: Pu Y 

PROVIDER: S-EPMC12583583 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature