Structural-functional fingerprinting for abnormalities investigation in glioma patients.

ABSTRACT: Gliomas alter brain function and integrity, but these disruptions are often studied separately. This study utilised a novel approach that integrated functional, structural and microstructural connectivity information to investigate glioma-induced brain network changes and their clinical implications. It focused on the impact of gliomas on key brain networks, with a particular emphasis on the relationship between tumour topology and its effect on homotopic areal-level parcellation. The investigation was grounded in a unique clinical dataset comprising functional and diffusion images of forty-one newly diagnosed glioma patients. Connectivity matrices (functional, structural, and microstructural) were generated using homotopic parcellations and combined into an integration connectivity matrix

SUBMITTER: Colpo M 

PROVIDER: S-EPMC12583605 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature