Safety of ribavirin in cockatiels (Nymphicus hollandicus) - a preliminary study.

ABSTRACT: Viral infections remain a major health concern in psittacine birds, with avian bornaviruses (ABV) causing proventricular dilatation disease (PDD), a chronic and often fatal condition. Ribavirin, a broad-spectrum antiviral drug widely used in human medicine, has shown in vitro (ABV) and in ovo (Newcastle disease virus) efficacy against some avian viruses, but its safety profile in birds is largely unknown. This study aimed to evaluate the safety of prolonged ribavirin administration in healthy cockatiels (Nymphicus hollandicus) aged approximately 6 months. The experiment consisted of experimental group (10 cockatiels) and negative control group (10 cockatiels). Ribavirin was administered to the experimental cockatiels according to the following protocol: orally (by gavage at dose 30 mg/kg b

SUBMITTER: Szotowska I 

PROVIDER: S-EPMC12583684 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature