Evaluating the long-term predictive value of macular thickness fluctuations on diabetic macular oedema response to anti-VEGF treatment.

ABSTRACT:

Objective

This study assesses the predictiveness of retinal thickness variability on long-term visual acuity (VA) outcomes in patients with diabetic macular oedema (DMO) undergoing anti-VEGF therapy.

Design

Retrospective chart review at a single institution.

Participants

184 and 138 patients underwent initial treatment for DMO and continued to follow-up at 3 and 5 years, respectively.

Methods

Baseline demographics, past medical, and clinical data were collected through electronic medical record query. Central subfield thickness (CST), choroidal volume (CV), and cube average thickness (CAT) variability over the first year of treatment were calculated using standard deviation, amplitude, and area under the curve. CST, CV, CAT, and best corrected visual acuity (BC

SUBMITTER: Alam T 

PROVIDER: S-EPMC12583765 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature