Acute high-intensity interval training, but not reduced-exertion high-intensity interval training increase brain-derived neurotrophic factor in a block randomized controlled trial.

ABSTRACT: Exercise has been linked to various physical and mental health benefits with neuroplasticity being one of the potential pathways. Brain-derived neurotrophic factor (BDNF) has emerged as one of the most researched factors relating to exercise induced neuroplasticity. As exercise intensity and work to rest ratio differ between various exercise protocols, comparison of high-intensity interval training (HIIT) and reduced exertion high-intensity interval training (REHIT) could indicate a more optimal protocol for neuroplasticity promotion. In this study, 60 low to moderately active young adults took part in a block-randomized clinical trial comparing how acute 15-minute-long HIIT and REHIT affect BDNF and lactate levels, while the control group watched a video. Lactate was measured before and i

SUBMITTER: Evelis K 

PROVIDER: S-EPMC12583766 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature