Identification of multidrug-resistant monophasic Salmonella Typhimurium ST34 and other NTS from animal-environmental origins in South Africa.

ABSTRACT: Non-typhoidal Salmonella (NTS) causes approximately 155 000 deaths annually and poses significant risks to both human and animal health. Antimicrobial resistance (AMR) in NTS is a growing global public health threat. Using a One Health approach, this study investigated NTS in swine, poultry, and wastewater in Gauteng Province, South Africa. From May 2019 to August 2020, 507 samples were collected, including animal faeces (n = 388), hand swabs (n = 104), abattoir and farm run-off (n = 10), and hospital (n = 1) and municipal wastewater (n = 4). Whole genome sequencing of recovered isolates revealed a 2.37% (12/507) NTS prevalence, identifying four serovars: Salmonella Enteritidis sequence type (ST) 11 (n = 3), S. Infantis ST32 (n = 4), S. Irumu ST2026 (n = 2), and multidrug-resistant S. Typh

SUBMITTER: Ogundare ST 

PROVIDER: S-EPMC12583814 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature