Synthesis of BODIPY-Linked N-Heterocyclic Carbene Metal Complexes for Cancer Chemotheranostics and Catalysis Applications.

ABSTRACT: Fluorescent N-heterocyclic carbene (NHC) metal complexes are useful for various chemical and biological applications. In this study, we developed a simple strategy to synthesize BODIPY-linked NHC metal complexes involving Ag, Cu, Ni, and Pd. The synthesis began with the preparation of BODIPY-imidazolium salt as a precursor ligand. This ligand was used to obtain BODIPY-imidazolium silver carbene complex, which subsequently facilitated the syntheses of BODIPY-linked NHC transition metal complexes (Cu, Ni, and Pd) via the transmetalation method. This approach offers a versatile pathway for the synthesis of various other fluorescent carbene metal complexes. The applications of these BODIPY-linked NHC metal complexes were also explored. Chemotherapeutic anti-cancer activity of BODIPY-imidazoliu

SUBMITTER: Yadav SS 

PROVIDER: S-EPMC12584020 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature