Optimizing Cancer Treatment: A Comprehensive Review of Active and Passive Drug Delivery Strategies.

ABSTRACT: Nanocarriers as powerful tools for delivering drugs to tumors provide new strategies for cancer treatment. These delivery systems encompass a diverse variety of structures, including polymeric nanoparticles (NPs), liposomes, dendrimers, micelles, and inorganic NPs such as gold and silica. Each type exhibits distinct physicochemical advantages that contribute to stability, drug-loading capacity, and targeting efficacy. Engineered nanocarriers can be utilized for the active targeting of tumor-specific receptors or for passive targeting of tumors via the enhanced permeability (EPR) and retention effect, a characteristic of abnormal tumor vasculature. This targeting approach enables the precise delivery of the therapeutic agents at tumor sites, increasing drug efficacy while minimizing exposur

SUBMITTER: Tarighi P 

PROVIDER: S-EPMC12584355 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature