Identification and functional characterization of the histone acetyltransferase gene family in Bursaphelenchus xylophilus.

ABSTRACT:

Background

Acetylation is a widely occurring post-translational protein modification in animals, plants, and microorganisms. Histone acetyltransferase (HATs) are positive regulators of acetylation and are responsible for the growth, development, and virulence of pathogens. The pine wood nematode (PWN) Bursaphelenchus xylophilus has caused extensive pine tree mortality, leading to significant loss in Asia; however, there is no HATs have been characterized in PWN.

Results

In the present study, 7 HATs in PWN were identified and grouped into 3 subfamilies with conserved protein structures and motif compositions. The RT-PCR analysis revealed that HAT expression levels varied across developmental, temperature, and infection stages in pines. After the interference of BxPCAF and BxE

SUBMITTER: Wang L 

PROVIDER: S-EPMC12584404 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature