UNLOADERS-PVAD Weaning Score: predicting post-weaning adverse events in cardiogenic shock patients supported by microaxial flow pump.

ABSTRACT:

Background

Limited data are available on risk stratification in patients undergoing weaning from percutaneous ventricular assist devices (PVADs). We aimed to identify factors associated with adverse events following PVAD weaning and to construct a predictive scoring system.

Methods

This study was a secondary analysis of the UNLOADERS-PVAD study, an observational registry involving three participating institutions in Japan. Consecutive patients with cardiogenic shock who received PVAD support were analyzed for 13 clinical and nine hemodynamic factors assessed immediately prior to PVAD explantation, using the least absolute shrinkage and selection operator (LASSO) method. Risk factors associated with 30-day events, defined as all-cause mortality or reintroduction of mechanical

SUBMITTER: Ikeda Y 

PROVIDER: S-EPMC12584505 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature