Non-linear relationship between the triglyceride glucose-a body shape index and stroke risk: a prospective cohort study from the China health and retirement longitudinal study.

ABSTRACT:

Objective

Recent evidence suggests a strong association between triglyceride glucose-a body shape index (TyG-ABSI) and cardiovascular mortality. However, the association between TyG-ABSI and incident stroke has not been explored. Our study utilized a prospective cohort design to explore the potential association between TyG-ABSI and incident stroke within a Chinese population.

Methods

A total of 8,715 subjects from the China Health and Retirement Longitudinal Study were included in this analysis, categorized into stroke (n = 805) and non-stroke (n = 7,910) groups. To assess the association between TyG-ABSI and incident stroke, this study employed Cox proportional hazards regression, restricted cubic spline models, subgroup analyses, and sensitivity analyses.

Results

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SUBMITTER: He D 

PROVIDER: S-EPMC12584527 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature