Use of rescue noninvasive ventilation for post-extubation respiratory failure.

ABSTRACT:

Background

Robust evidence supports the use of preemptive non-invasive ventilation (NIV) after extubation in selected high-risk patient cohorts. In contrast, current guidelines discourage the use of NIV as a rescue therapy for respiratory failure that develops later after extubation, based on earlier studies indicating a potential increase in hospital mortality due to delayed reintubation. Nonetheless, NIV continues to be employed in this setting. We conducted a post-hoc analysis of a randomized trial to assess the clinical outcomes of rescue NIV for post-extubation respiratory failure.

Methods

In this post-hoc analysis of a randomized trial comparing high-flow with Venturi mask oxygen in hypoxemic patients after extubation, we included those who developed post-extubation re

SUBMITTER: Grieco DL 

PROVIDER: S-EPMC12584535 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature