Gut microbiome and atrial fibrillation: mechanistic insights metabolites and comorbidities. Systematic review.

ABSTRACT: Emerging evidence indicates that the gut microbiome (GM) and its metabolites may play a role in the development of cardiometabolic diseases, including atrial fibrillation (AF). Although the current data are limited, studies suggest that the GM composition in AF mirrors that observed in associated conditions such as heart failure, hypertension, diabetes, and coronary artery disease (characterized by increased genera Lactobacillus, Enterococcus, Streptococcus, and decreased genus Faecalibacterium). Additionally, patients with AF appear to have distinct microbial alterations, including increased abundances of the genera Dialister, Dorea, Haemophilus, Klebsiella, Lachnospira, Parabacteroides, Ruminococcus, and Veillonella and decreased abundances of the genera Bu

SUBMITTER: Gawalko M 

PROVIDER: S-EPMC12584657 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature