Urogenital microbiome, intracellular bacterial communities, and their contribution to urinary tract infections.

ABSTRACT: The urinary tract was long considered a sterile environment, but recent studies have revealed the presence of diverse microbial communities in healthy individuals collectively known as the urinary microbiome or urobiome. Although the urobiome has been studied primarily in populations from North America, Europe, and Asia, little is known about its characteristics in Latin America. In this work, we conducted a descriptive analysis of the urobiome of 77 adults, 40 females, and 37 males with and without symptoms of urinary tract infections (UTI) from Uruguay using a strategy that includes expanded quantitative uroculture, 16S rRNA gene sequencing from urine, and intracellular bacterial community evaluation. The microbial profiles revealed a wide diversity in the bacterial community composition

SUBMITTER: Robino L 

PROVIDER: S-EPMC12584659 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature