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Decoding anaerobes: a comprehensive evaluation of MALDI-TOF Sirius and VITEK MS PRIME in clinical settings.


ABSTRACT: The timely identification of anaerobic bacteria at the genus and species levels is critical for managing infections and guiding antimicrobial therapy. Matrix-assisted laser desorption-ionization time-of-flight (MALDI-TOF) mass spectrometry (MS) has emerged as a powerful tool for the identification of anaerobic bacteria, overcoming challenges associated with their special culture requirements and low growth rates. This technique has proven to be both reliable and efficient, providing accurate identification with minimal bacterial biomass. The application of MALDI-TOF MS in clinical settings has significantly improved the identification of anaerobic bacteria, facilitating appropriate treatment decisions and enhancing patient outcomes with minor costs. This study evaluates the performance of

SUBMITTER: Rocca MF 

PROVIDER: S-EPMC12584683 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature