Performance analysis of the GeneXpert respiratory panel prototype assay for the diagnosis of viral and bacterial upper respiratory tract infections.

ABSTRACT: GeneXpert respiratory panel (GX-RP) is a new in vitro qualitative multiplexed nucleic acid amplification test designed to simultaneously detect and identify 26 common respiratory pathogens from nasopharyngeal swabs (NPSs) in patients exhibiting signs and symptoms of upper respiratory tract infection. This is a retrospective study that compares the prototype assay with two FDA-approved respiratory panels-the BioFire FilmArray (FA) Respiratory 2.1 plus and Hologic Panther Fusion (PF) respiratory assay. A total of 292 NPS specimens from patients with upper respiratory tract infection symptoms were collected from three hospitals in Hong Kong, SAR. There was concordance in 269/292 specimens (92.1%), reaching full agreement with Influenza A, Bordetella pertussis, and Mycoplasma

SUBMITTER: Chan LMW 

PROVIDER: S-EPMC12584745 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature