Abdominal computed tomography-assessed muscle quality and its prognostic value in patients with advanced chronic kidney disease initiating hemodialysis.

ABSTRACT:

Background

Skeletal muscle density (SMD), assessed via L3 level computed tomography (CT), is a critical marker of muscle quality with remarkable prognostic value in various clinical settings. This study investigates prognostic values of the SMD of abdominal CT images and to verifies its relationship with other variables indicating sarcopenia in patients with advanced chronic kidney disease (CKD) patients.

Methods

All 458 patients initiating hemodialysis for maintenance were enrolled in this retrospective study. The sex-specific cut-off values of the SMD and skeletal muscle index (SMI) of L3 level abdominal CT were obtained by drawing the receiver operating characteristic curve for mortality. Cut-offs for identifying low SMD and SMI groups were applied.

Results

The mea

SUBMITTER: Han S 

PROVIDER: S-EPMC12585029 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature