Predictive value of neutrophil to lymphocyte ratio for clinical outcomes in liver cirrhosis: A systematic review and meta-analysis.

ABSTRACT:

Background

The neutrophil-to-lymphocyte ratio (NLR) is a simple yet potent marker that has been established as an independent predictor of mortality in patients with cirrhosis. However, consensus is lacking regarding its prognostic value for predicting mortality risk in these patients. Therefore, we conducted a meta-analysis to clarify its clinical significance.

Methods

We performed a literature search in PubMed, Web of Science, Cochrane Library, and Embase for studies published from database inception until January 1, 2025. Studies focusing on the diagnosis of cirrhosis were included, while those involving children and neonates were excluded. Odds ratio (OR) and its 95% confidence interval (CI) were calculated using the random-effects model. Sensitivity analysis was conduct

SUBMITTER: Lin J 

PROVIDER: S-EPMC12585051 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature