Financial risk protection from vaccines in 52 Gavi-eligible low- and middle-income countries: A modeling study.

ABSTRACT:

Background

Poverty alleviation is a major global development goal. Vaccines have the potential to provide financial risk protection (FRP) by preventing illnesses and associated healthcare costs. We estimate the lifetime FRP benefits generated by major vaccines among individuals vaccinated between 2000 and 2030 in low- and middle-income countries (LMICs).

Methods and findings

We developed a microsimulation model to quantify the number of cases of catastrophic health expenditure (CHE) averted by a range of vaccines in 52 Gavi-eligible countries, stratified by wealth quintile. Vaccines protecting against five pathogens were considered, i.e., hepatitis B (routine and birth dose vaccine), Haemophilus influenzae type B, rotavirus, measles (routine and supplementary campaign vaccin

SUBMITTER: Jiao B 

PROVIDER: S-EPMC12585062 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature