The relationship between the neutrophil percentage to albumin ratio and the occurrence of prostate cancer.

ABSTRACT:

Background

Although prior research has indicated that nutritional and inflammatory markers may play a role in prostate cancer development, the exact interplay and underlying mechanisms are not yet fully understood.

Materials and methods

The study population comprised 16,481 males from the NHANES database, after excluding participants with missing covariates. The Neutrophil Percentage-to-Albumin Ratio (NPAR) was used to assess the inflammation and nutritional status. Statistical methods such as multivariable logistic regression, eXtreme Gradient Boosting model, subgroup analysis, and Generalized Additive Model were used to analyze the relationship between NPAR and prostate cancer prevalence.

Results

The restricted cubic splines of the independent variable NPAR and the

SUBMITTER: Kong P 

PROVIDER: S-EPMC12585082 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature