Green synthesis of silver nanoparticles from Brownlowia tersa leaf extract: multifaceted evaluation of antibacterial, antioxidant, cytotoxic, and anti-alzheimer potential.

ABSTRACT: This study reports the first green synthesis of silver nanoparticles (AgNPs) using an aqueous leaf extract of Brownlowia tersa (B. tersa), confirming their formation via UV-Vis spectrophotometry with a peak at 472 nm. The AgNPs were evaluated for their antimicrobial and neuroprotective activities, particularly for Alzheimer's disease. GC-MS and FT-IR analyses identified phenolics and flavonoids as the capping and reducing agents in the synthesis process. FESEM imaging showed nanoparticles of varied shapes and sizes, while EDX analysis confirmed the presence of silver, oxygen, and carbon. The antimicrobial activity was demonstrated with inhibition zones ranging from 8.5 to 10.5 mm against Staphylococcus aureus, Bacillus cereus, Shigella flexneri, and Pseudomonas aeruginosa at concentrations

SUBMITTER: Hossain MR 

PROVIDER: S-EPMC12585095 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature