Real-Time Predictive Analysis of ICU Ventilator Weaning Failure: A Prospective Validation Study.

ABSTRACT:

Objective

To construct and validate a nomogram model for predicting the risk of ICU ventilator weaning failure (reintubation or death within 48 h after extubation) based on multidimensional clinical indicators.

Methods

A total of 485 patients in the ICU who needed ventilator weaning were selected and divided into a training set (n = 340) and a validation set (n = 145) at a ratio of 7:3. Baseline data and weaning-related indicators of the patients were collected. Weaning failure (reintubation or death within 48 h after weaning) was regarded as the outcome event. Independent risk factors were screened through univariate and multivariate logistic regression. A nomogram model was constructed, and the model's performance was evaluated using the C-index, AUC, calibration curve, Ho

SUBMITTER: Zhou L 

PROVIDER: S-EPMC12585916 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature