Identification and genetic characterization of porcine rotavirus A in Haryana, India: molecular diversity and relationship with human rotavirus A.

ABSTRACT: Rotavirus A (RVA; family Sedoreoviridae, taxon species Rotavirus alphagastroenteritidis) is a non-enveloped double-stranded RNA virus that has been reported from both diarrheic and non-diarrheic pigs worldwide. With significant morbidity and mortality rates in neonatal piglets, rotavirus-associated illness adds enormous economic losses to the pig industry. Furthermore, the proximity of humans and pigs facilitates cross-species infection, which results in the formation of novel strains through genetic recombination. We aimed to detect and characterize porcine RVA (PRVA) in Haryana, India, using reverse-transcription PCR targeting the VP6, VP4, and VP7 genes. We detected 46 of 137 (34%) rectal swab samples as positive for PRVA, including 27 of 63 (43%) from

SUBMITTER: Sheoran D 

PROVIDER: S-EPMC12586386 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature