Octadecanoids as emerging lipid mediators in cnidarian-dinoflagellate symbiosis.

ABSTRACT: Oxylipin signaling has been suggested as a potential mechanism for the inter-partner recognition and homeostasis regulation of cnidarian-dinoflagellate symbiosis, which maintains the ecological viability of coral reefs. Here we assessed the effects of symbiosis and symbiont identity on a model cnidarian, the sea anemone Exaiptasia diaphana, using mass spectrometry to quantify octadecanoid oxylipins (i.e., 18-carbon-derived oxygenated fatty acids). A total of 84 octadecanoids were reported, and distinct stereospecificity was observed for the synthesis of R- and S-enantiomers for symbiont-free anemones and free-living cultured dinoflagellate symbionts, respectively. Symbiont-derived 13(S)-hydroxy-octadecatetraenoic acid (13(S)-HOTE) linked to a putative 13(S)-lipoxygenase was translocated to

SUBMITTER: Botana MT 

PROVIDER: S-EPMC12586643 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature