Aromatic C-H hydroxylation reactions catalysed by nickel(ii) complexes of monoanionic ligands.

ABSTRACT: The selective conversion of benzene to phenol in a single step under mild reaction conditions could serve as a viable alternative to the cumene process. Herein, we report the catalytic activity of nickel(ii) complexes of the type [Ni(L)(H₂O)]ClO₄ (1-3) containing monoamidate pentadentate N5 ligands (L1(H)-L3(H)) in the oxidation of aromatic C-H bonds using H₂O₂ as the oxidant. Catalytic conditions were optimised by studying the effect of catalyst loading, H₂O₂ amount, temperature and reaction time. Among the series, catalyst 1 showed the best activity under optimised reaction conditions with a phenol yield of 24.6%, selectivity of 98%, and a turnover number (TON) of 492. Ligand donor moiety influence on the catalytic perform

SUBMITTER: Rajeev A 

PROVIDER: S-EPMC12587151 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature