Patterns of comorbidities, clinical course, and impact of the ABC Pathway for Integrated Care in patients with atrial fibrillation: a report from the prospective Optimal Thromboprophylaxis in Elderly Chinese Patients with Atrial Fibrillation (ChiOTEAF) Registry.

ABSTRACT:

Aims

To identify comorbidity patterns in elderly Chinese patients with atrial fibrillation (AF), their clinical course, and the effectiveness of the Atrial fibrillation Better Care (ABC) pathway adherence among these phenotypes.

Methods and results

From the ChiOTEAF Registry, we performed a latent class analysis based on 16 cardiovascular (CV) and non-CV conditions. The association between classes of patients, management, and outcomes was evaluated. The primary outcome was a composite of all-cause death and major adverse CV events. We assessed the impact of ABC adherence on outcomes in the whole cohort and among phenotypes. We included 4765 AF patients [median age 77 (68-83) years, 39.1% females]. Four phenotypes were identified: (i) low complexity (48.9%); (ii) atherosclero

SUBMITTER: Mantovani M 

PROVIDER: S-EPMC12587286 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature