Stroke onset time affected outcomes in the young acute ischemic stroke patients treated with endovascular thrombectomy.

ABSTRACT:

Objective

The purpose of this study was to investigate the association between stroke onset time and prognosis after endovascular thrombectomy (EVT) in Acute Ischemic Stroke (AIS) patients at different ages.

Methods

The AIS patients who underwent endovascular thrombectomy (EVT) between August 2018 to June 2022 were collected retrospectively. The patients were divided into two onset time groups [day-onset (6:00 h-18:00 h) vs. night-onset (18:00 h-6:00 h)], and further divided into 4 onset age groups (< 55 y, 55-64 y, 65-74 y and 75+ y). The primary outcome was discharge National Institutes of Health Stroke Scale (NIHSS) score and secondary outcomes were malignant brain edema, hemorrhagic transformation (HT), and early vascular recanalization (mTICI ≥ 2b). Mediation analyses w

SUBMITTER: Yu M 

PROVIDER: S-EPMC12588849 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature