Antimicrobial effects of essential oil from <i>Origanum vulgare</i> in combination with conventional antibiotics against <i>Staphylococcus aureus</i>.

ABSTRACT:

Background

Antimicrobial resistance is emerging as a significant threat to public health, prompting the search for novel natural molecules, such as Essential Oils (EOs), that can affect, alone or in combination with conventional antibiotics, growth and various biological activities in microorganisms.

Methods

First, the effects of ten essential oils extracted from aromatic plants grown in Calabria (Southern Italy) and seven conventional antibiotics against Staphylococcus aureus cells were studied individually, determining the Minimum Inhibitory Concentrations (MICs) through broth microdilutions. Subsequently, limited to Origanum vulgare EO (OEO) only, the compounds were evaluated in combination through checkerboard and time kill assays. ZIP synergy scores and Fr

SUBMITTER: De Rose E 

PROVIDER: S-EPMC12588934 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature