Inelastic mechanical descriptors for osteoporotic hip fracture discrimination with 3D-DXA-based nonlinear finite element models.

ABSTRACT:

Introduction

Dual-energy X-ray absorptiometry (DXA) is the gold standard for diagnosing osteoporosis. Advances in 2D-3D modelling to generate patient-specific 3D-DXA models out of DXA images enable accurate volumetric representations of the femur, with potential for fracture risk prediction when combined with finite element (FE) analyses. This study evaluates the ability of 3D-DXA-based FE models to discriminate hip fractures under side-fall loading.

Methods

We used a retrospective case-control study including 128 women, 64 of whom suffered a hip fracture. Mechanical descriptors, including strength, nonlinear deformation, residual displacement, and energy absorption under elastic-plastic assumptions, were derived from force-displacement curves.

Results

The area under

SUBMITTER: Alizadeh E 

PROVIDER: S-EPMC12589097 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature