Crystal structures of the dimethyl sulfoxide solvate of 3,6-bis-(indol-3-yl)-1,4-di-methyl-piperazine-2,5-dione and of the dimethyl sulfoxide and tetra-hydro-furan solvates of 1,4-dimethyl-3,6-bis-(2-methyl-indol-3-yl)piperazine-2,5-dione.

ABSTRACT: The syntheses and structures of the dimethyl sulfoxide (DMSO) solvate of 3,6-bis-(indol-3-yl)-1,4-di-methyl-piperazine-2,5-dione, C₁₁H₁₀N₂O (I), and of the dimethyl sulfoxide and tetra-hydro-furan (THF) solvates of 1,4-dimethyl-3,6-bis-(2-methyl-indol-3-yl)piperazine-2,5-dione, C₁₂H₁₂N₂O, (II) and (III), respectively, are reported. The asymmetric units of (I) and (II) each contain two crystallographically independent half-mol-ecules that are completed by inversion symmetry, whereas (III) contains one independent half-mol-ecule. In all three structures, the piperazine-2,5-dione core is essentially planar and the overall mol-ecular non-planarity arises from rotations of the indole subs

SUBMITTER: Padgett CW 

PROVIDER: S-EPMC12589834 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature