Superparamagnetic MnFe₂O₄@Fe₂O₃ lipid-coated small nanoparticles: Synthesis, physicochemical characterization and biocompatibility assessment in drosophila melanogaster.

ABSTRACT: Magnetic nanoparticles (MNPs), particularly manganese ferrite (MnFe₂O₄), have emerged as promising candidates for biomedical applications due to their tunable magnetic properties, biocompatibility, and functionalization potential. In this study, we synthesized superparamagnetic MnFe₂O₄@Fe₂O₃ core-shell nanoparticles (5.8 nm inorganic core, ∼10 nm lipid-coated) functionalized with oleic acid (OA) or soy lecithin (Lec) to enhance biocompatibility. To the best of our knowledge, this work is the first to combine this unique hybrid core-shell structure with lipid coatings and evaluate its safety in an animal model. To characterize the MNPs we provided structural, magnetic, and physical-chemistry studies using transmission electro

SUBMITTER: Perez AS 

PROVIDER: S-EPMC12589892 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature