Hepatoprotective effects of silibinin and chlorogenic acid standardised extract to alleviate the fatty liver syndrome and improve blood indices in caged-laying hens after the peak of production.

ABSTRACT: This study was designed to assess the effectiveness of a mixture of Silybum marianum L. and Cynara cardunculus scolymus L. standardised extract (PHYTO-LAYER™) expressed as silibinin (2.4 g/L) and chlorogenic acid (2.2 g/L) content, respectively, provided intermittently to caged-laying hens to alleviate fatty liver syndromes, improve blood indices and health. In this study, 792 Lohmann LSL-White hens (41 weeks of age), randomly assigned to 2 replicated groups, control and treated (n = 396 each), were used. The treatment (1 mL/L) was supplied every 2 weeks for 7 days, at different time points (T0-T5) in a 7-week trial, by drinking water. At T0, T3 and T5, 13 identified hens/group were sampled for haematological analysis. At T5, all 13 hens per group were euthanised via c

SUBMITTER: Guerrini A 

PROVIDER: S-EPMC12589915 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature