Statin Use in Patients With Cancer: Drug Interaction and Statin Usage.

ABSTRACT:

Background

Cardiovascular disease and cancer share common risk factors. Statins, which are widely prescribed for cardiovascular disease prevention, have potential for drug-drug interactions (DDIs) with oncology agents.

Objectives

This study quantifies and characterizes interactions between statins and recently approved oncology agents. Additionally, the study evaluates statin prescribing trends in patients with cancer.

Methods

Food and Drug Administration oncology drug approvals from June 2019 to June 2024 were screened for interactions with 5 commonly prescribed statins using UpToDate Lexidrug. Interaction severity was classified into 5 risk levels. Statin prescribing rates, stratified by cancer type, were characterized through a scoping review of 20 PubMed-indexed o

SUBMITTER: Chou E 

PROVIDER: S-EPMC12589975 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature