Evaluating shock index for prediction of adverse maternal outcomes related to postpartum haemorrhage and maternal sepsis in Sierra Leone: a prospective observational cohort study.

ABSTRACT:

Background

Postpartum haemorrhage (PPH) and sepsis account for more than half of global maternal deaths. Shock index (SI), the ratio of heart rate to systolic blood pressure, has shown superior prediction of adverse outcomes compared to other vital signs, but most studies are retrospective, with limited evidence in sepsis. We aimed to prospectively evaluate SI for adverse outcome prediction in PPH and sepsis.

Methods

This prospective cohort study was undertaken between March 2022 and July 2023 in three hospitals in Sierra Leone, in 495 and 855 women with PPH or sepsis respectively. 'First' and 'worst' SI measured in each woman was compared to other vital signs, including modified shock index (MSI), for prediction of outcomes (maternal death; major procedure; lowest haemoglob

SUBMITTER: Kuhrt K 

PROVIDER: S-EPMC12590223 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature