VP1 region-based molecular characterization of foot-and-mouth disease virus serotype O from clinical cases in Haryana, India.

ABSTRACT:

Background

Foot-and-mouth disease (FMD) is a highly transmissible viral infection affecting cloven-hoofed animals, significantly impacting livestock productivity and trade in India. The causative agent, FMD virus (FMDV), exhibits considerable genetic and antigenic diversity, with serotype O being most prevalent. Haryana, a northern Indian state with a large susceptible livestock population, has reported sporadic FMD cases despite ongoing vaccination efforts. This study aims to detect, type, and characterize FMDV from suspected animals in Haryana during 2024, with a focus on genetic variations in the VP1 region compared to the vaccine strain and contemporary isolates.

Results

Clinical samples from suspected cases were analyzed using RT-multiplex PCR, confirming the presence o

SUBMITTER: Dalal P 

PROVIDER: S-EPMC12590671 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature