Accurate profiling of microbial communities for shotgun metagenomic sequencing with Meteor2.

ABSTRACT:

Background

The characterization of complex microbial communities is a critical challenge in microbiome research, as it is essential for understanding the intricate relationships between microorganisms and their environments. Metagenomic profiling has advanced into a multifaceted approach, combining taxonomic, functional, and strain-level profiling (TFSP) of microbial communities. Here, we present Meteor2, a tool that leverages compact, environment-specific microbial gene catalogues to deliver comprehensive TFSP insights from metagenomic samples.

Results

Meteor2 currently supports 10 ecosystems, gathering 63,494,365 microbial genes clustered into 11,653 metagenomic species pangenomes (MSPs). These genes are extensively annotated for KEGG orthology, carbohydrate-active enzymes

SUBMITTER: Ghozlane A 

PROVIDER: S-EPMC12590682 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature