Radiological characteristics for guiding intra-arterial therapy in intermediate-stage hepatocellular carcinoma.

ABSTRACT:

Background

To evaluate and contrast the efficacy and safety of trans-arterial chemoembolization (TACE) versus hepatic arterial infusion chemotherapy (HAIC) for intermediate-stage hepatocellular carcinoma (HCC) based on varying radiologic patterns.

Methods

A retrospective study identified 3,060 consecutive patients with intermediate-stage HCC who underwent initial TACE or HAIC between January 2009 and December 2022. HCC radiological features were categorized into pseudo-capsulated, pseudocapsule breakthrough, confluent multinodular, and infiltrative types. The propensity score matching (PSM) method was employed to minimize selection bias. The progression-free survival (PFS) was compared using the Kaplan-Meier method with the log-rank test. Independent prognostic factors were

SUBMITTER: An C 

PROVIDER: S-EPMC12590844 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature