Ultrafast breast DCE-MRI: comparative analysis of semi-quantitative and pharmacokinetic parameters with gadoterate meglumine versus gadobutrol in malignant lesions and background parenchymal enhancement.

ABSTRACT:

Background

There is increasing interest in high temporal resolution imaging techniques in breast magnetic resonance imaging (MRI) for breast cancer detection. The purpose of this study was to compare diagnostic performance and kinetic characteristics of gadoterate meglumine (Dotarem^®) and gadobutrol (Gadavist^®) in ultrafast breast dynamic contrast-enhanced MRI (DCE-MRI), focusing on semi-quantitative and pharmacokinetic parameters for differentiating malignant lesions from background parenchymal enhancement (BPE).

Methods

Ultrafast DCE-MRI acquisition is a high temporal resolution (3.5-4.6 seconds) imaging technique used during the first minute following contrast injection to obtain three-dimensional (3D) whole breast images. All ultrafast images were m

SUBMITTER: Chumsaengsri S 

PROVIDER: S-EPMC12591752 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature