Comparative analysis of the geometric morphology and local hemodynamics of small and medium intracranial aneurysms: a two-center retrospective study in a Chinese Han population.

ABSTRACT:

Background

Small (<4 mm) and medium (≥4 and <15 mm) intracranial aneurysms (IAs) account for the majority of lesions detected on routine cerebrovascular imaging, yet their true rupture propensity and mechanistic pathways remain controversial, particularly in Asian populations. Emerging evidence indicates that geometry-dependent hemodynamic disturbances may modulate rupture risk, but size-specific patterns have not been systematically compared. Therefore, we aimed to compare the clinical, geometric, and hemodynamic characteristics of small and medium IAs and to clarify the rupture-related mechanisms.

Methods

We retrospectively reviewed computed tomography angiography (CTA) and digital subtraction angiography (DSA) in 214 patients with ruptured or unruptured IAs. Geometric par

SUBMITTER: Cui X 

PROVIDER: S-EPMC12591785 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature