The utility of multi-b-value diffusion and arterial spin labelling magnetic resonance imaging in gliomas grading and prediction of isocitrate dehydrogenase status.

ABSTRACT:

Background

Although the possibilities for grading adult gliomas by conventional magnetic resonance imaging (MRI) are limited, several advanced techniques may be used in this respect. In this study, we evaluate the feasibility of multi-b-value diffusion MRI and arterial spin labelling (ASL) in grading gliomas and predicting their isocitrate dehydrogenase (IDH) molecular status.

Methods

Preoperative brain MRI including multi-b-value diffusion sequences and ASL was performed prospectively in patients with gliomas. Three-dimensional (3D) masks of tumours were semi-automatically segmented and multiple diffusion parameters and cerebral blood flow (CBF) maps calculated. Histogram analysis of all parameters was performed and the parameters' diagnostic power to differentiate between

SUBMITTER: Koprivova T 

PROVIDER: S-EPMC12591914 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature