Untargeted metabolomic analysis of dietary rumen-protected choline supplementation in fattening lambs.

ABSTRACT:

Introduction

Choline is an essential nutrient that plays a key role in lipid metabolism and growth performance in livestock.

Methods

This study investigated the effects of rumen-protected choline (RPC) supplementation on serum metabolite profiles in fattening lambs. Twenty 3-month-old hybrid rams (Small-Tailed Han × Northeast Fine-Wool; initial body weight: 15.3 ± 1.8 kg) were randomly assigned to two groups (n = 10 each): a control group (CON; 0 g RPC/kg dry matter [DM]) and an RPC group (5 g RPC/kg DM). Over a 122-day feeding period, lambs were provided ad libitum access to feed and water, with feedings at 08:00 and 15:00 daily. Serum samples were collected at the end of the trial and analyzed using untargeted metabolomics based on liquid chromatography-tande

SUBMITTER: Yun J 

PROVIDER: S-EPMC12591947 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature