Ophthalmic artery flow reversal and pressure reducing carotid stenosis.

ABSTRACT:

Background

In the United States (US), 80,000 strokes annually are attributed to carotid stenosis among the 140,000,000 people over age 40 years old. More than 300,000 people in the US have severe carotid stenosis. Most of those people have normal cerebral perfusion pressure to each portion of the brain because the circle of Willis (coW) provides collateral connection between the basilar artery and the two carotid arteries. In those cases, a reduction in flow through one carotid artery does not affect brain perfusion. However, about 75,000 people with severe carotid stenosis also have a disconnected coW resulting in a pressure reducing carotid stenosis and regional reduced cerebral perfusion pressure. Currently, in standard medical care, every carotid stenosis is treated aggressivel

SUBMITTER: Brown B 

PROVIDER: S-EPMC12592005 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature