Comparison of ziprasidone and olanzapine on cognitive function in patients with schizophrenia at different stages: a prospective study in Huai'an, China.

ABSTRACT:

Objective

To compare the effects of ziprasidone and olanzapine on cognitive function in patients with first-episode schizophrenia and chronic schizophrenia at different stages.

Methods

Cognitive function tests were performed on chronic schizophrenic patients who took olanzapine for a long time, first-episode drug-free schizophrenic patients, and healthy controls.

Results

There were significant differences in the digit span test, Stroop color and word test, auditory verbal learning test N2, N3, N4, trail-making test, verbal fluency test, and clock drawing test between first-episode drug-free schizophrenic patients and healthy controls (p < 0.05). Compared with patients with chronic schizophrenia, there were significant differences in the digit span test, Stroop

SUBMITTER: Yao J 

PROVIDER: S-EPMC12592029 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature