Clinical symptom improvement and lipidomic signatures in overweight/obese PCOS treated by lifestyle and acupuncture intervention.

ABSTRACT:

Background

Polycystic ovary syndrome (PCOS) is interrelated with obesity. Lifestyle intervention, mainly focusing on weight loss, has emerged as promising strategies to improve fertility outcomes in women with obesity. Acupuncture can aid in weight loss through metabolic regulation. However, evaluating the effectiveness of lifestyle and acupuncture in improving symptoms of polycystic ovary syndrome is still lacking.

Results

This study aims to evaluate the efficacy of long-term lifestyle and acupuncture treatment on PCOS and elucidate the lipidomic features of these interventions in patients with overweight/obese PCOS, and identify potential therapeutic targets. Thirty-one women with PCOS and twenty-eight age and BMI matched controls were recruited. The participants with PCOS

SUBMITTER: Zhang H 

PROVIDER: S-EPMC12592129 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature