Development of siRNA therapeutics to combat microbial infections: a bibliometric analysis.

ABSTRACT:

Background

The rise of antimicrobial resistance and the COVID-19 pandemic highlight the limitations of traditional therapies. Small interfering RNA (siRNA) therapeutics, which utilize RNA interference for targeted gene silencing, present a promising approach to combating microbial infections. However, research in this area remains fragmented. This study employs a comprehensive bibliometric analysis to chart research trends and inform future directions.

Methods

A total of 8,426 publications from the Web of Science Core Collection (2001-2025) were analyzed using CiteSpace and VOSviewer software to examine annual publication trends, geographic and institutional contributions, author networks, journal impacts, and keyword evolution. Data extraction focused on English-language ar

SUBMITTER: He Y 

PROVIDER: S-EPMC12592196 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature