Neural correlates of depression-related smartphone language use in adolescents.

ABSTRACT: Magnetic resonance imaging has provided pathophysiological insights into adolescent depression but is a relatively inaccessible technology. Generating scalable indicators of depression that are informed by neuroscience is therefore critical for providing solutions that allow us to detect and treat this devastating disorder. In this preregistered study, we investigated whether passively acquired smartphone-based language usage represents such an indicator of depression and explored whether the neural correlates of depression mediate or moderate this association. Forty adolescents (ages 14-18 years) with (n = 26) and without (n = 14) depression completed clinical assessments and a resting-state fMRI scan, prior to downloading a passive mobile sensing app to their smartphones. L

SUBMITTER: McNeilly EA 

PROVIDER: S-EPMC12592214 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature